We have the answer for Main vein crossword clue in case you’ve been struggling to solve this one! Crossword puzzles can be an excellent way to stimulate your brain, pass the time, and challenge yourself all at once. Of course, sometimes there’s a crossword clue that totally stumps us, whether it’s because we are unfamiliar with the subject matter entirely or we just are drawing a blank.
Now, let's get into the answer for Main vein crossword clue most recently seen in the Universal Crossword.
Main vein Crossword Clue Answer is…
Answer: MOTHERLODE
This clue last appeared in the Universal Crossword on March 18, 2024. You can also find answers to past Universal Crosswords.
Related Universal Crossword Answers

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Clue & Answer Definitions
- VEIN (noun)
- a blood vessel that carries blood from the capillaries toward the heart
- one of the horny ribs that stiffen and support the wing of an insect
- VEIN (verb)
- make a veinlike pattern
- MAIN (adjective)
- (of a clause) capable of standing syntactically alone as a complete sentence
- most important element
- MAIN (noun)
- any very large body of (salt) water
- a principal pipe in a system that distributes water or gas or electricity or that collects sewage
Historical Usage in Crossword Puzzles
About the Universal Crossword
The Universal Crossword is a daily crossword puzzle that is syndicated to newspapers and online publications around the world. The puzzle is created by a team of experienced crossword constructors, who are known for their skill and creativity in the field of crossword puzzles.

The Universal Crossword was first introduced in 1999, and has since become a popular source of entertainment and mental stimulation for crossword enthusiasts of all ages. The puzzle is known for its clever clues and challenging difficulty level, and is updated daily with new and interesting themes.
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